Restriction Fragment Length Polymorphism (RFLP) and Polymerase Chain Reaction Short Tandem Repeat (PRR/STR) are two types of DNA testing currently used for paternity and family reconstruction testing. In specific instances other types of DNA testing may also be used.
Restriction Fragment Length Polymorphism (RFLP) testing was the most frequent type of DNA tests used until the late 1990s. Because of the expense and time involved with RFLP testing, it is no longer performed by most DNA laboratories.
Even though it is slow and labor intensive, RFLP testing is a very powerful test. A typical RFLP location is many times more powerful than a typical PCR/STR location.
For an identity case, STR/PCR is more than adequate for comparing one specimen to another and for most paternity cases it is quite dependable. But, for difficult paternity testing and for family reconstruction cases, STR/PCR testing is often inadequate to provide a reliable answer.
Cases that cannot be solved using PCR/STR testing are often easily solved with RFLP testing. The much more powerful RFLP can change an inconclusive PCR/STR case into a very reliable and conclusive test.
Before choosing a laboratory for your paternity test, ask what additional testing the laboratory will provide if a reliable answer is not obtained from initial testing. If there is no minimum guarantee and if there are additional charges for extended testing, then look for another laboratory.
It is possible to hire a laboratory that will guarantee you a minimum probability of paternity of 99.99% money back guarantee. If a laboratory will not give you this written guarantee, then they probably do not have adequate testing available to ensure that they can give a reliable answer on your test.
Always ask for a money back guarantee when ordering a paternity test. If the laboratory is confident in their abilities, they should be happy to accommodate you. If they will not provide a written guarantee, then look for another laboratory.
Restriction Fragment Length Polymorphism (RFLP) testing was the most frequent type of DNA tests used until the late 1990s. Because of the expense and time involved with RFLP testing, it is no longer performed by most DNA laboratories.
Even though it is slow and labor intensive, RFLP testing is a very powerful test. A typical RFLP location is many times more powerful than a typical PCR/STR location.
For an identity case, STR/PCR is more than adequate for comparing one specimen to another and for most paternity cases it is quite dependable. But, for difficult paternity testing and for family reconstruction cases, STR/PCR testing is often inadequate to provide a reliable answer.
Cases that cannot be solved using PCR/STR testing are often easily solved with RFLP testing. The much more powerful RFLP can change an inconclusive PCR/STR case into a very reliable and conclusive test.
Before choosing a laboratory for your paternity test, ask what additional testing the laboratory will provide if a reliable answer is not obtained from initial testing. If there is no minimum guarantee and if there are additional charges for extended testing, then look for another laboratory.
It is possible to hire a laboratory that will guarantee you a minimum probability of paternity of 99.99% money back guarantee. If a laboratory will not give you this written guarantee, then they probably do not have adequate testing available to ensure that they can give a reliable answer on your test.
Always ask for a money back guarantee when ordering a paternity test. If the laboratory is confident in their abilities, they should be happy to accommodate you. If they will not provide a written guarantee, then look for another laboratory.
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